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Systematic name YAL032C
Gene name PRP45
Aliases FUN20
Feature type ORF, Verified
Coordinates Chr I:84474..83335
Primary SGDID S000000030

Description of YAL032C: Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene[1][2][3]


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  1. Albers M, et al. (2003) Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors. RNA 9(1):138-50 SGD PMID 12554883
  2. Figueroa JD and Hayman MJ (2004) The human Ski-interacting protein functionally substitutes for the yeast PRP45 gene. Biochem Biophys Res Commun 319(4):1105-9 SGD PMID 15194481
  3. Martinkova K, et al. (2002) Functional mapping of Saccharomyces cerevisiae Prp45 identifies the SNW domain as essential for viability. J Biochem 132(4):557-63 SGD PMID 12359070

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