YAL015C
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| Systematic name | YAL015C |
| Gene name | NTG1 |
| Aliases | FUN33, SCR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:128103..126904 |
| Primary SGDID | S000000013 |
Description of YAL015C: DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair; distribution between nucleus and mitochondrion varies according to which compartment is under oxidative stress and is also sumoylation-dependent[1][2][3]
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References
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- ↑ Griffiths LM, et al. (2009) Dynamic compartmentalization of base excision repair proteins in response to nuclear and mitochondrial oxidative stress. Mol Cell Biol 29(3):794-807 SGD PMID 19029246
- ↑ Meadows KL, et al. (2003) Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function. Nucleic Acids Res 31(19):5560-7 SGD PMID 14500818
- ↑ Alseth I, et al. (1999) The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast. Mol Cell Biol 19(5):3779-87 SGD PMID 10207101
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