YAL001C

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Systematic name YAL001C
Gene name TFC3
Aliases FUN24, TSV115
Feature type ORF, Verified
Coordinates I:151168..147596


Description of YAL001C: Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding[1][2][3][4]




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References

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  1. Schultz P, et al. (1989) The two DNA-binding domains of yeast transcription factor tau as observed by scanning transmission electron microscopy. EMBO J 8(12):3815-24 SGD PMID 2684647
  2. Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26 SGD PMID 11419933
  3. Conesa C, et al. (1993) On the subunit composition, stoichiometry, and phosphorylation of the yeast transcription factor TFIIIC/tau. J Biol Chem 268(24):18047-52 SGD PMID 7688737
  4. Lefebvre O, et al. (1992) TFC3: gene encoding the B-block binding subunit of the yeast transcription factor IIIC. Proc Natl Acad Sci U S A 89(21):10512-6 SGD PMID 1279682

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