RDN5-1
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| Systematic name | RDN5-1 |
| Gene name | RDN5-1 |
| Aliases | RDN5 |
| Feature type | rRNA |
| Coordinates | Chr XII:459676..459796 |
| Primary SGDID | S000006479 |
Description of RDN5-1: 5S ribosomal RNA (5S rRNA); only complete sequence of 6 repeated RDN5 alleles; able to support viability when provided as sole form of 5S rRNA; component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in translational frame fidelity; transcription is mediated by PolIII and activated by TFIIIA and TFIIIE[1][2][3][4][5]
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References
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- ↑ Camier S, et al. (1995) The only essential function of TFIIIA in yeast is the transcription of 5S rRNA genes. Proc Natl Acad Sci U S A 92(20):9338-42 SGD PMID 7568129
- ↑ Dieci G, et al. (2009) Positive modulation of RNA polymerase III transcription by ribosomal proteins. Biochem Biophys Res Commun 379(2):489-93 SGD PMID 19116144
- ↑ Dinman JD and Wickner RB (1995) 5 S rRNA is involved in fidelity of translational reading frame. Genetics 141(1):95-105 SGD PMID 8536994
- ↑ Kiparisov S, et al. (2005) Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae. Mol Genet Genomics 274(3):235-47 SGD PMID 16047201
- ↑ Michael WM and Dreyfuss G (1996) Distinct domains in ribosomal protein L5 mediate 5 S rRNA binding and nucleolar localization. J Biol Chem 271(19):11571-4 SGD PMID 8626719
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