Difference between revisions of "Chromosome VII History"

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Old    397196  TGTTAAACAATTCATGTCTCCCGGAAAATTCTCCACAGGCAAAGAAGTTAGCTGGTGCTT  397255</pre>
 
Old    397196  TGTTAAACAATTCATGTCTCCCGGAAAATTCTCCACAGGCAAAGAAGTTAGCTGGTGCTT  397255</pre>
 +
Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
 +
 +
|- style="height:30px; width:30px; text-align:center;"
 +
| 2011-02-03
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| YGR058W
 +
| 607109
 +
| 607109
 +
| Substitution
 +
| T
 +
| G
 +
|-
 +
| || colspan="6" | A single nucleotide substitution within the coding region of PEF1/YGR058W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 324 is now Aspartic Acid rather than Tyrosine.
 +
<pre>New    607062  TAATCAAGAAGGCATTGCAACCATACAGTACAAAGATTTTATCGATGCTACATTATATTT  607121
 +
                ||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
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Old    607066  TAATCAAGAAGGCATTGCAACCATACAGTACAAAGATTTTATCTATGCTACATTATATTT  607125</pre>
 +
Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
 +
 +
|- style="height:30px; width:30px; text-align:center;"
 +
| rowspan="3"| 2011-02-03
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| rowspan="3"| YGR271W
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| 1033108
 +
| 1033108
 +
| Substitution
 +
| C
 +
| T
 +
|- style="height:30px; width:30px; text-align:center;"
 +
| 1032373
 +
| 1032373
 +
| Substitution
 +
| G
 +
| A
 +
|- style="height:30px; width:30px; text-align:center;"
 +
| 1031948
 +
| 1031948
 +
| Substitution
 +
| C
 +
| A
 +
|-
 +
| || colspan="6" | Nucleotide substitutions within the coding region of SLH1/YGR271W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 51 is now Glutamine rather than Proline, residue 193 is now Lysine rather than Glutamic Acid, and residue 438 is now Serine rather than Proline.
 +
<pre>New    1031905  TTTGATGACGAGCTAAAAAAAGTCCAAAAGGATGAACAAAATCAAAGAACTGAACTAACT  1031964
 +
                ||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||
 +
Old    1031911  TTTGATGACGAGCTAAAAAAAGTCCAAAAGGATGAACCAAATCAAAGAACTGAACTAACT  1031970
 +
 +
New    1032325  CCAGAGTTCCTGACACAGCAAGATATCAGGAATCAAGTTTTGAAAAGTGCAGAGGATGCC  1032384
 +
                |||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
 +
Old    1032331  CCAGAGTTCCTGACACAGCAAGATATCAGGAATCAAGTTTTGGAAAGTGCAGAGGATGCC  1032390
 +
 +
New    1033055  AATTACTAATTATTGATGAAGTTCATTTACTGCACGAAGATAGAGGTTCGGTTATTGAAA  1033114
 +
                ||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
 +
Old    1033061  AATTACTAATTATTGATGAAGTTCATTTACTGCACGAAGATAGAGGTCCGGTTATTGAAA  1033120</pre>
 
Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
 
Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

Revision as of 10:25, 27 September 2019

This page lists all sequence and annotation changes that have been made to the Chromosome VII systematic reference sequence since its intial release on 1996-07-31. The sequence of Chromosome VII has been updated 125 times, affecting 87 features. The annotation of Chromosome VII has been updated 54 times, affecting 88 features.

Sequence Changes

Date Affected Features Start Coordinate of Change End Coordinate of Change Type of Change Old Sequence New Sequence
2011-02-03 YGR067C 622408 622408 Substitution A T
A single nucleotide substitution was made in the stop codon of ORF YGR067C, destroying it and increasing the length of the annotated protein by 10 amino acids.
New    622362   TCTTTGGCCATTATTTTATTTGGCTAAAAATTTCAATGTTTTTACTTTGTTTATTGTCAG  622421
                |||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old    622366   TCTTTGGCCATTATTTTATTTGGCTAAAAATTTCAATGTTTTAACTTTGTTTATTGTCAG  622425

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGL197W 125909 125910 Substitution CG GC
125487 125487 Insertion A
125495 125495 Deletion A
Nucleotide changes within the coding region of MDS3/YGL197W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 262-264 are now QSE rather than HPK, and residue 403 is now Alanine rather than Arginine.
New    125449   TAGACATCTATAACATCTCACAGAATTGCTGGCAATCCGAAA-CCATACCCAAACAACCG  125507
                |||||||||||||||||||||||||||||||||| ||||||| |||||||||||||||||
Old    125454   TAGACATCTATAACATCTCACAGAATTGCTGGCA-TCCGAAAACCATACCCAAACAACCG  125512

New    125868   ATATACGATATTAACTCCGGAAAGTGGTCACGAGTCGCTACCGCCTGCCCTGACTGCGAT  125927
                ||||||||||||||||||||||||||||||||||||  ||||||||||||||||||||||
Old    125873   ATATACGATATTAACTCCGGAAAGTGGTCACGAGTCCGTACCGCCTGCCCTGACTGCGAT  125932

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGL041C, YGL041W-A 419056 419056 Deletion G
A single nucleotide was deleted within the coding regions of overlapping ORFs YGL041W-A and YGL041C, resulting in altered protein sequences for both ORFs. The YGL041W-A C-terminus and majority of the reading frame remain the same, but the N-terminus has changed and the annotated protein is now 72 amino acids longer. The YGL041C N-terminus remains the same, but the C-terminus has changed and the annotated protein is truncated by one-third of its length (reduced from 104 amino acids to 67 amino acids).
New    419013   ACTCATGGATCAAATAAATTCGAGGCCTAATGTTCTGG-AAAAGTTAGAAAAGGTTAGCA  419071
                |||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old    419018   ACTCATGGATCAAATAAATTCGAGGCCTAATGTTCTGGGAAAAGTTAGAAAAGGTTAGCA  419077

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGL214W 90019 90019 Insertion T
A single T nucleotide was inserted within ORF YGL214W very near its 5' end, altering its coding sequence. The reading frame and stop remain the same, but the start has been shifted downstream four nucleotides and the annotated protein is now one amino acid shorter.
New    89994    CCAAAAAGAATAATGGATGATTGTAAGGTTACATGCAATATATCAAGATATTACTAGAGA  90053
                ||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old    89999    CCAAAAAGAATAATGGATGAT-GTAAGGTTACATGCAATATATCAAGATATTACTAGAGA  90057

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGL129C 269097 269097 Deletion A
A single nucleotide was deleted within ORF RSM23/YGL129C, altering its coding sequence. The C-terminus and majority of the reading frame remain the same, but the N-terminus has changed and the annotated protein is now 38 amino acids shorter.
New    269076   TATTCTGATACGTATA-CCACGTGGCTTGTACTTGTTCTCTTGTTAATGTTTTCCCTCGA  269134
                |||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
Old    269081   TATTCTGATACGTATAACCACGTGGCTTGTACTTGTTCTCTTGTTAATGTTTTCCCTCGA  269140

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGL056C 397085 397086 Substitution CG GC
397241 397241 Substitution A C
Nucleotide changes within the coding region of SDS23/YGL056C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 180 is now Glycine rather than Alanine.
New    397060   GTGTCAACTTTACTATCTCGCCCACGGGCACGGACTTACCATTCTGGCAGTCTGAGGTTA  397119
                |||||||||||||||||||  |||||||||||||||||||||||||||||||||||||||
Old    397066   GTGTCAACTTTACTATCTCCGCCACGGGCACGGACTTACCATTCTGGCAGTCTGAGGTTA  397125

New    397190   TGTTAAACAATTCATGTCTCCCGGAAAATTCTCCACAGGCAAAGACGTTAGCTGGTGCTT  397249
                ||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Old    397196   TGTTAAACAATTCATGTCTCCCGGAAAATTCTCCACAGGCAAAGAAGTTAGCTGGTGCTT  397255

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGR058W 607109 607109 Substitution T G
A single nucleotide substitution within the coding region of PEF1/YGR058W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 324 is now Aspartic Acid rather than Tyrosine.
New    607062   TAATCAAGAAGGCATTGCAACCATACAGTACAAAGATTTTATCGATGCTACATTATATTT  607121
                ||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old    607066   TAATCAAGAAGGCATTGCAACCATACAGTACAAAGATTTTATCTATGCTACATTATATTT  607125

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGR271W 1033108 1033108 Substitution C T
1032373 1032373 Substitution G A
1031948 1031948 Substitution C A
Nucleotide substitutions within the coding region of SLH1/YGR271W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 51 is now Glutamine rather than Proline, residue 193 is now Lysine rather than Glutamic Acid, and residue 438 is now Serine rather than Proline.
New    1031905  TTTGATGACGAGCTAAAAAAAGTCCAAAAGGATGAACAAAATCAAAGAACTGAACTAACT  1031964
                ||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||
Old    1031911  TTTGATGACGAGCTAAAAAAAGTCCAAAAGGATGAACCAAATCAAAGAACTGAACTAACT  1031970

New    1032325  CCAGAGTTCCTGACACAGCAAGATATCAGGAATCAAGTTTTGAAAAGTGCAGAGGATGCC  1032384
                |||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old    1032331  CCAGAGTTCCTGACACAGCAAGATATCAGGAATCAAGTTTTGGAAAGTGCAGAGGATGCC  1032390

New    1033055  AATTACTAATTATTGATGAAGTTCATTTACTGCACGAAGATAGAGGTTCGGTTATTGAAA  1033114
                ||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old    1033061  AATTACTAATTATTGATGAAGTTCATTTACTGCACGAAGATAGAGGTCCGGTTATTGAAA  1033120

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98