YPR005C

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Systematic name YPR005C
Gene name HAL1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:566671..565787
Primary SGDID S000006209


Description of YPR005C: Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p[1][2][3][4]




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References

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  1. Gaxiola R, et al. (1992) A novel and conserved salt-induced protein is an important determinant of salt tolerance in yeast. EMBO J 11(9):3157-64 SGD PMID 1505513
  2. Marquez JA, et al. (1998) The Ssn6-Tup1 repressor complex of Saccharomyces cerevisiae is involved in the osmotic induction of HOG-dependent and -independent genes. EMBO J 17(9):2543-53 SGD PMID 9564037
  3. Pascual-Ahuir A, et al. (2001) The Sko1p repressor and Gcn4p activator antagonistically modulate stress-regulated transcription in Saccharomyces cerevisiae. Mol Cell Biol 21(1):16-25 SGD PMID 11113177
  4. Rios G, et al. (1997) Mechanisms of salt tolerance conferred by overexpression of the HAL1 gene in Saccharomyces cerevisiae. Yeast 13(6):515-28 SGD PMID 9178503

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