YPL132W

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Systematic name YPL132W
Gene name COX11
Aliases LPI13, PSO7
Feature type ORF, Verified
Coordinates Chr XVI:301716..302618
Primary SGDID S000006053


Description of YPL132W: Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p[1][2][3]




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References

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  1. Hiser L, et al. (2000) Cox11p is required for stable formation of the Cu(B) and magnesium centers of cytochrome c oxidase. J Biol Chem 275(1):619-23 SGD PMID 10617659
  2. Khalimonchuk O, et al. (2005) Evidence for the association of yeast mitochondrial ribosomes with Cox11p, a protein required for the Cu(B) site formation of cytochrome c oxidase. Curr Genet 47(4):223-33 SGD PMID 15776235
  3. Tzagoloff A, et al. (1990) Cytochrome oxidase assembly in yeast requires the product of COX11, a homolog of the P. denitrificans protein encoded by ORF3. EMBO J 9(9):2759-64 SGD PMID 2167832

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