YOR058C
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Systematic name | YOR058C |
Gene name | ASE1 |
Aliases | YOR29-09 |
Feature type | ORF, Verified |
Coordinates | Chr XV:436345..433688 |
Primary SGDID | S000005584 |
Description of YOR058C: Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate[1][2][3]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [4] [5]
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [6]
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References
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- ↑ Juang YL, et al. (1997) APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science 275(5304):1311-4 SGD PMID 9036857
- ↑ Schuyler SC, et al. (2003) The molecular function of Ase1p: evidence for a MAP-dependent midzone-specific spindle matrix. Microtubule-associated proteins. J Cell Biol 160(4):517-28 SGD PMID 12591913
- ↑ 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
SGD PMID 14574415 Cite error: Invalid
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tag; name "S000074306" defined multiple times with different content - ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
- ↑ submitted by Jeff Ubersax on 2004-01-29
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