YNL206C

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Systematic name YNL206C
Gene name RTT106
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:258155..256788
Primary SGDID S000005150


Description of YNL206C: Histone chaperone, involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition[1][2][3][4]




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References

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  1. Fillingham J, et al. (2009) Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression. Mol Cell 35(3):340-51 SGD PMID 19683497
  2. Huang S, et al. (2005) Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing. Proc Natl Acad Sci U S A 102(38):13410-5 SGD PMID 16157874
  3. Imbeault D, et al. (2008) The rtt106 histone chaperone is functionally linked to transcription elongation and is involved in the regulation of spurious transcription from cryptic promoters in yeast. J Biol Chem 283(41):27350-4 SGD PMID 18708354
  4. Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 SGD PMID 11779788

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