YMR264W

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Systematic name YMR264W
Gene name CUE1
Aliases KIS4
Feature type ORF, Verified
Coordinates Chr XIII:795805..796416
Primary SGDID S000004877


Description of YMR264W: Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination[1][2]




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References

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  1. ↑ Biederer T, et al. (1997) Role of Cue1p in ubiquitination and degradation at the ER surface. Science 278(5344):1806-9 SGD PMID 9388185
  2. ↑ Shih SC, et al. (2003) A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J 22(6):1273-81 SGD PMID 12628920

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