YML120C
Share your knowledge...Edit this entry! <protect>
| Systematic name | YML120C |
| Gene name | NDI1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:29807..28266 |
| Primary SGDID | S000004589 |
Description of YML120C: NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; involved in Mn and H2O2 induced apoptosis; under stress, N-terminus of Ndi1p is cleaved to be activated within mitochondria and the truncated Ndi1p translocates to cytoplasm to perform apoptosis; homolog of human AMID[1][2][3][4][5]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- ↑ Cui Y, et al. (2012) Mitochondrial Release of the NADH Dehydrogenase Ndi1 Induces Apoptosis in Yeast. Mol Biol Cell () SGD PMID 22993213
- ↑ Li W, et al. (2006) Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging. Mol Biol Cell 17(4):1802-11 SGD PMID 16436509
- ↑ Marres CA, et al. (1991) Isolation and inactivation of the nuclear gene encoding the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. Eur J Biochem 195(3):857-62 SGD PMID 1900238
- ↑ Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
- ↑ Velazquez I and Pardo JP (2001) Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. Arch Biochem Biophys 389(1):7-14 SGD PMID 11370674
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
