YML001W

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Systematic name YML001W
Gene name YPT7
Aliases AST4, VAM4
Feature type ORF, Verified
Coordinates Chr XIII:267174..267800
Primary SGDID S000004460


Description of YML001W: Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7[1][2][3][4][5]




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References

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  1. Jump up Collins KM, et al. (2005) Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion. EMBO J 24(10):1775-86 SGD PMID 15889152
  2. Jump up Haas A, et al. (1995) The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance. EMBO J 14(21):5258-70 SGD PMID 7489715
  3. Jump up Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 SGD PMID 22593205
  4. Jump up Schimmoller F and Riezman H (1993) Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast. J Cell Sci 106 ( Pt 3):823-30 SGD PMID 8308065
  5. Jump up Wichmann H, et al. (1992) Endocytosis in yeast: evidence for the involvement of a small GTP-binding protein (Ypt7p). Cell 71(7):1131-42 SGD PMID 1473149

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