YLR397C
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| Systematic name | YLR397C |
| Gene name | AFG2 |
| Aliases | DRG1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:914892..912550 |
| Primary SGDID | S000004389 |
Description of YLR397C: ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; may be involved in degradation of aberrant mRNAs[1][2][3]
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References
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- ↑ Pertschy B, et al. (2007) Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1. Mol Cell Biol 27(19):6581-92 SGD PMID 17646390
- ↑ Thorsness PE, et al. (1993) AFG2, an essential gene in yeast, encodes a new member of the Sec18p, Pas1p, Cdc48p, TBP-1 family of putative ATPases. Yeast 9(11):1267-71 SGD PMID 8109176
- ↑ Zakalskiy A, et al. (2002) Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization. J Biol Chem 277(30):26788-95 SGD PMID 12006565
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