YLR089C
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| Systematic name | YLR089C |
| Gene name | ALT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:320015..318237 |
| Primary SGDID | S000004079 |
Description of YLR089C: Alanine transaminase (glutamic pyruvic transaminase); involved in alanine biosynthetic and catabolic processes; expression is induced in the presence of alanine; repression is mediated by Nrg1p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; paralogous gene ALT2 is catalytically inactive[1][2][3][4]
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References
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- ↑ Blank LM, et al. (2005) Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts. FEMS Yeast Res 5(6-7):545-58 SGD PMID 15780654
- ↑ Garcia-Campusano F, et al. (2009) ALT1-encoded alanine aminotransferase plays a central role in the metabolism of alanine in Saccharomyces cerevisiae. Can J Microbiol 55(4):368-74 SGD PMID 19396236
- ↑ Penalosa-Ruiz G, et al. (2012) Paralogous ALT1 and ALT2 Retention and Diversification Have Generated Catalytically Active and Inactive Aminotransferases in Saccharomyces cerevisiae. PLoS One 7(9):e45702 SGD PMID 23049841
- ↑ Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
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