YLR043C

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Systematic name YLR043C
Gene name TRX1
Aliases LMA1
Feature type ORF, Verified
Coordinates Chr XII:232013..231702
Primary SGDID S000004033


Description of YLR043C: Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance[1][2][3][4][5][6][7]




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References

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  1. Jump up Barlowe C (1997) Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol 139(5):1097-108 SGD PMID 9382859
  2. Jump up Garrido EO and Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides. Mol Microbiol 43(4):993-1003 SGD PMID 11929546
  3. Jump up Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 SGD PMID 10037727
  4. Jump up Spang A and Schekman R (1998) Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol 143(3):589-99 SGD PMID 9813082
  5. Jump up Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 SGD PMID 12410842
  6. Jump up Xu Z and Wickner W (1996) Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 132(5):787-94 SGD PMID 8603912
  7. Jump up Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 SGD PMID 9015301

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