YJL208C
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| Systematic name | YJL208C |
| Gene name | NUC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:41183..40194 |
| Primary SGDID | S000003744 |
Description of YJL208C: Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy[1][2][3][4][5]
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References
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- ↑ Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 SGD PMID 17471024
- ↑ Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 SGD PMID 17244531
- ↑ Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 SGD PMID 3286639
- ↑ Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 SGD PMID 2836792
- ↑ Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 SGD PMID 8087883
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