YJL127C
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| Systematic name | YJL127C |
| Gene name | SPT10 |
| Aliases | CRE1, SUD1 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:184220..182298 |
| Primary SGDID | S000003663 |
Description of YJL127C: Putative histone acetylase with a role in transcriptional silencing, sequence-specific activator of histone genes, binds specifically and cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box[1][2][3][4]
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References
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- ↑ Chang JS and Winston F (2011) Spt10 and Spt21 Are Required for Transcriptional Silencing in Saccharomyces cerevisiae. Eukaryot Cell 10(1):118-29 SGD PMID 21057056
- ↑ Eriksson PR, et al. (2005) Global regulation by the yeast Spt10 protein is mediated through chromatin structure and the histone upstream activating sequence elements. Mol Cell Biol 25(20):9127-37 SGD PMID 16199888
- ↑ Shen CH, et al. (2002) Targeted histone acetylation at the yeast CUP1 promoter requires the transcriptional activator, the TATA boxes, and the putative histone acetylase encoded by SPT10. Mol Cell Biol 22(18):6406-16 SGD PMID 12192040
- ↑ Yamashita I (1993) Isolation and characterization of the SUD1 gene, which encodes a global repressor of core promoter activity in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):616-26 SGD PMID 8264536
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