YHR178W

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Systematic name YHR178W
Gene name STB5
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:459299..461530
Primary SGDID S000001221


Description of YHR178W: Transcription factor, involved in regulating multidrug resistance and oxidative stress response; forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a pleiotropic drug resistance element in vitro[1][2][3]




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References

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  1. Akache B, et al. (2004) Complex interplay among regulators of drug resistance genes in Saccharomyces cerevisiae. J Biol Chem 279(27):27855-60 SGD PMID 15123673
  2. Kasten MM and Stillman DJ (1997) Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Mol Gen Genet 256(4):376-86 SGD PMID 9393435
  3. Larochelle M, et al. (2006) Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production. Mol Cell Biol 26(17):6690-701 SGD PMID 16914749

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