YHR064C
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| Systematic name | YHR064C |
| Gene name | SSZ1 |
| Aliases | PDR13 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:227141..225525 |
| Primary SGDID | S000001106 |
Description of YHR064C: Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP[1][2][3]
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References
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- ↑ Eisenman HC and Craig EA (2004) Activation of pleiotropic drug resistance by the J-protein and Hsp70-related proteins, Zuo1 and Ssz1. Mol Microbiol 53(1):335-44 SGD PMID 15225326
- ↑ Hallstrom TC and Moye-Rowley WS (2000) Hyperactive forms of the Pdr1p transcription factor fail to respond to positive regulation by the hsp70 protein Pdr13p. Mol Microbiol 36(2):402-13 SGD PMID 10792726
- ↑ Huang P, et al. (2005) The Hsp70 Ssz1 modulates the function of the ribosome-associated J-protein Zuo1. Nat Struct Mol Biol 12(6):497-504 SGD PMID 15908962
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