YER049W
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| Systematic name | YER049W |
| Gene name | TPA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:251728..253662 |
| Primary SGDID | S000000851 |
Description of YER049W: Poly(rA)-binding protein involved in translation termination efficiency, mRNA poly(A) tail length and mRNA stability; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; similar to prolyl 4-hydroxylases; binds Fe(III) and 2-oxoglutarate[1][2]
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References
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- ↑ Keeling KM, et al. (2006) Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae. Mol Cell Biol 26(14):5237-48 SGD PMID 16809762
- ↑ Kim HS, et al. (2010) Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex. Nucleic Acids Res 38(6):2099-110 SGD PMID 20040577
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