YDR481C
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| Systematic name | YDR481C |
| Gene name | PHO8 |
| Aliases | phoH |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1420250..1418550 |
| Primary SGDID | S000002889 |
Description of YDR481C: Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN[1][2][3]
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References
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- ↑ Donella-Deana A, et al. (1993) Specific dephosphorylation of phosphopeptides by the yeast alkaline phosphatase encoded by PHO8 gene. Biochim Biophys Acta 1177(2):221-8 SGD PMID 8499492
- ↑ Kaneko Y, et al. (1985) Transcriptional and post-transcriptional control of PHO8 expression by PHO regulatory genes in Saccharomyces cerevisiae. Mol Cell Biol 5(1):248-52 SGD PMID 2984552
- ↑ Klionsky DJ and Emr SD (1989) Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J 8(8):2241-50 SGD PMID 2676517
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