YDR390C
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| Systematic name | YDR390C |
| Gene name | UBA2 |
| Aliases | UAL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1256847..1254937 |
| Primary SGDID | S000002798 |
Description of YDR390C: Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability[1][2]
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References
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- ↑ Dohmen RJ, et al. (1995) An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. J Biol Chem 270(30):18099-109 SGD PMID 7629121
- ↑ Johnson ES, et al. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J 16(18):5509-19 SGD PMID 9312010
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