YDR190C
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| Systematic name | YDR190C |
| Gene name | RVB1 |
| Aliases | TIH1, TIP49, TIP49A |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:841995..840604 |
| Primary SGDID | S000002598 |
Description of YDR190C: ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly[1][2][3][4][5][6][7][8][9][10][11][12]
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References
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- ↑ Gribun A, et al. (2008) Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex. J Mol Biol 376(5):1320-33 SGD PMID 18234224
- ↑ Jonsson ZO, et al. (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem 276(19):16279-88 SGD PMID 11278922
- ↑ Jonsson ZO, et al. (2004) Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. Mol Cell 16(3):465-77 SGD PMID 15525518
- ↑ Kakihara Y and Houry WA (2011) The R2TP complex: Discovery and functions. Biochim Biophys Acta () SGD PMID 21925213
- ↑ King TH, et al. (2001) A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins. Mol Cell Biol 21(22):7731-46 SGD PMID 11604509
- ↑ Krogan NJ, et al. (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76 SGD PMID 14690608
- ↑ Mizuguchi G, et al. (2004) ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303(5656):343-8 SGD PMID 14645854
- ↑ Qiu XB, et al. (1998) An eukaryotic RuvB-like protein (RUVBL1) essential for growth. J Biol Chem 273(43):27786-93 SGD PMID 9774387
- ↑ Shen X, et al. (2000) A chromatin remodelling complex involved in transcription and DNA processing. Nature 406(6795):541-4 SGD PMID 10952318
- ↑ Torreira E, et al. (2008) Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. Structure 16(10):1511-20 SGD PMID 18940606
- ↑ Zhao R, et al. (2005) Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone. Cell 120(5):715-27 SGD PMID 15766533
- ↑ Zhao R, et al. (2008) Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. J Cell Biol 180(3):563-78 SGD PMID 18268103
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