YDL139C
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| Systematic name | YDL139C |
| Gene name | SCM3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:212046..211375 |
| Primary SGDID | S000002298 |
Description of YDL139C: Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones, required for kinetochore assembly; required for G2/M progression and localization of Cse4p; may protect Cse4p from ubiquitylation[1][2][3][4]
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References
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- ↑ Aravind L, et al. (2007) Domain architectures of the Scm3p protein provide insights into centromere function and evolution. Cell Cycle 6(20):2511-5 SGD PMID 17704645
- ↑ Chen Y, et al. (2000) The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain. Mol Cell Biol 20(18):7037-48 SGD PMID 10958698
- ↑ Hewawasam G, et al. (2010) Psh1 Is an E3 Ubiquitin Ligase that Targets the Centromeric Histone Variant Cse4. Mol Cell 40(3):444-54 SGD PMID 21070970
- ↑ Stoler S, et al. (2007) Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization. Proc Natl Acad Sci U S A 104(25):10571-6 SGD PMID 17548816
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