YBL105C
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Systematic name | YBL105C |
Gene name | PKC1 |
Aliases | CLY15, HPO2, STT1 |
Feature type | ORF, Verified |
Coordinates | Chr II:17696..14241 |
Primary SGDID | S000000201 |
Description of YBL105C: Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- ↑ Andrews PD and Stark MJ (2000) Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth. J Cell Sci 113 ( Pt 15):2685-93 SGD PMID 10893184
- ↑ Levin DE, et al. (1994) Dissecting the protein kinase C/MAP kinase signalling pathway of Saccharomyces cerevisiae. Cell Mol Biol Res 40(3):229-39 SGD PMID 7874200
- ↑ Watanabe M, et al. (1994) Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC. J Biol Chem 269(24):16829-36 SGD PMID 8207005
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
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