YAL040C
(Redirected from DAF1)
Share your knowledge...Edit this entry! <protect>
| Systematic name | YAL040C |
| Gene name | CLN3 |
| Aliases | DAF1, FUN10, WHI1 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:67520..65778 |
| Primary SGDID | S000000038 |
Description of YAL040C: G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis[1][2][3]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
<protect>
References
See Help:References on how to add references
- ↑ Cross FR and Blake CM (1993) The yeast Cln3 protein is an unstable activator of Cdc28. Mol Cell Biol 13(6):3266-71 SGD PMID 8497251
- ↑ Nash R, et al. (1988) The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog. EMBO J 7(13):4335-46 SGD PMID 2907481
- ↑ Tyers M, et al. (1992) The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. EMBO J 11(5):1773-84 SGD PMID 1316273
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
