YIL043C

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Systematic name YIL043C
Gene name CBR1
Aliases CBR5
Feature type ORF, Verified
Coordinates Chr IX:274925..274071
Primary SGDID S000001305


Description of YIL043C: Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia[1][2][3][4]




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References

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  1. Nussenzveig RH, et al. (2006) A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica 91(11):1542-5 SGD PMID 17082011
  2. Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
  3. Csukai M, et al. (1994) Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae. Eur J Biochem 219(1-2):441-8 SGD PMID 8307010
  4. Kubota S, et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J Biochem 81(1):187-95 SGD PMID 14930

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