YPL058C
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| Systematic name | YPL058C | |
| Gene name | PDR12 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XVI:450374..445839 | |
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Description of YPL058C: Plasma membrane weak-acid-inducible ATP-binding cassette (ABC) transporter, required for weak organic acid resistance, strongly induced by sorbate and benzoate, regulated by War1p, mutants exhibit sorbate hypersensitivity[1][2][3]
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References
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- ↑ Schuller C, et al. (2004) Global phenotypic analysis and transcriptional profiling defines the weak acid stress response regulon in Saccharomyces cerevisiae. Mol Biol Cell 15(2):706-20 SGD PMID 14617816
- ↑ Holyoak CD, et al. (1999) The Saccharomyces cerevisiae weak-acid-inducible ABC transporter Pdr12 transports fluorescein and preservative anions from the cytosol by an energy-dependent mechanism. J Bacteriol 181(15):4644-52 SGD PMID 10419965
- ↑ Holyoak CD, et al. (2000) Loss of Cmk1 Ca(2+)-calmodulin-dependent protein kinase in yeast results in constitutive weak organic acid resistance, associated with a post-transcriptional activation of the Pdr12 ATP-binding cassette transporter. Mol Microbiol 37(3):595-605 SGD PMID 10931353
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