YPL004C

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Systematic name YPL004C
Gene name LSP1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:551654..550629
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Description of YPL004C: Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p ; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways[1][2]



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References

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  1. Walther TC, et al. (2006) Eisosomes mark static sites of endocytosis. Nature 439(7079):998-1003 SGD PMID 16496001
  2. Zhang X, et al. (2004) Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p. J Biol Chem 279(21):22030-8 SGD PMID 15016821

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