YOR173W
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| Systematic name | YOR173W | |
| Gene name | DCS2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XV:657265..658326 | |
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Description of YOR173W: Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, similar to Dcs1p.[1][2][3][4]
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References
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- ↑ Malys N and McCarthy JE (2006) Dcs2, a Novel Stress-induced Modulator of m(7)GpppX Pyrophosphatase Activity that Locates to P Bodies. J Mol Biol 363(2):370-82 SGD PMID 16963086
- ↑ Malys N, et al. (2004) The 'scavenger' m7GpppX pyrophosphatase activity of Dcs1 modulates nutrient-induced responses in yeast. Nucleic Acids Res 32(12):3590-600 SGD PMID 15240832
- ↑ Liu H, et al. (2002) The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J 21(17):4699-708 SGD PMID 12198172
- ↑ Tadi D, et al. (1999) Selection of genes repressed by cAMP that are induced by nutritional limitation in Saccharomyces cerevisiae. Yeast 15(16):1733-45 SGD PMID 10590462
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