YDR103W
Revision as of 13:05, 17 September 2007 by SGDwikiBot (talk | contribs) (Automated import of articles)
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR103W |
| Gene name | STE5 |
| Aliases | HMD3, NUL3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:658347..661100 |
| Primary SGDID | S000002510 |
Description of YDR103W: Pheromone-response scaffold protein; binds kinases Ste11p, Ste7p, and Fus3p to form a MAPK cascade complex that interacts with the plasma membrane, via a PH (pleckstrin homology) and PM/NLS domain, and with Ste4p-Ste18p, during signaling[1][2][3][4][5]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- ↑ Garrenton LS, et al. (2006) Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain. Genes Dev 20(14):1946-58 SGD PMID 16847350
- ↑ Winters MJ, et al. (2005) A membrane binding domain in the ste5 scaffold synergizes with gbetagamma binding to control localization and signaling in pheromone response. Mol Cell 20(1):21-32 SGD PMID 16209942
- ↑ Kranz JE, et al. (1994) The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev 8(3):313-27 SGD PMID 8314085
- ↑ Printen JA and Sprague GF Jr (1994) Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138(3):609-19 SGD PMID 7851759
- ↑ Choi KY, et al. (1999) Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell 10(5):1553-68 SGD PMID 10233162
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
