YOL126C

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Systematic name YOL126C
Gene name MDH2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:82920..81787
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Description of YOL126C: Cytoplasmic malate dehydrogenase, one of the three isozymes that catalyze interconversion of malate and oxaloacetate; involved in gluconeogenesis during growth on ethanol or acetate as carbon source; interacts with Pck1p and Fbp1p[1][2]



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References

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  1. Gibson N and McAlister-Henn L (2003) Physical and genetic interactions of cytosolic malate dehydrogenase with other gluconeogenic enzymes. J Biol Chem 278(28):25628-36 SGD PMID 12730240
  2. Minard KI and McAlister-Henn L (1991) Isolation, nucleotide sequence analysis, and disruption of the MDH2 gene from Saccharomyces cerevisiae: evidence for three isozymes of yeast malate dehydrogenase. Mol Cell Biol 11(1):370-80 SGD PMID 1986231

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