YNL229C
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| Systematic name | YNL229C |
| Gene name | URE2 |
| Aliases | [URE3] |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:220202..219138 |
| Primary SGDID | S000005173 |
Description of YNL229C: Nitrogen catabolite repression regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion[1][2][3]
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Contents
Community Commentary
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Ure2p is composed of 354 amino acids. The first approximately 90 residues form a prion domain that is necessary for the formation and propagation of the prion. The c-terminal domain is the Nitrogen Catabolite Repression (NCR) domain, which is required for repression of genes involved in nitrogen catabolism.
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References
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- ↑ Wickner RB (1994) [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. Science 264(5158):566-9 SGD PMID 7909170
- ↑ Blinder D, et al. (1996) Interaction of the GATA factor Gln3p with the nitrogen regulator Ure2p in Saccharomyces cerevisiae. J Bacteriol 178(15):4734-6 SGD PMID 8755910
- ↑ Courchesne WE and Magasanik B (1988) Regulation of nitrogen assimilation in Saccharomyces cerevisiae: roles of the URE2 and GLN3 genes. J Bacteriol 170(2):708-13 SGD PMID 2892826
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