YOL052C

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Systematic name YOL052C
Gene name SPE2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:233635..232445
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Description of YOL052C: S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically[1][2]



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References

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  1. Kashiwagi K, et al. (1990) Spermidine biosynthesis in Saccharomyces cerevisiae. Biosynthesis and processing of a proenzyme form of S-adenosylmethionine decarboxylase. J Biol Chem 265(36):22321-8 SGD PMID 2266128
  2. Balasundaram D, et al. (1991) Spermidine or spermine is essential for the aerobic growth of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 88(13):5872-6 SGD PMID 2062864

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