YNR057C
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| Systematic name | YNR057C | |
| Gene name | BIO4 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XIV:734069..733356 | |
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Description of YNR057C: Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels[1][2]
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References
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- ↑ Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 SGD PMID 14668481
- ↑ Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51 SGD PMID 10333520
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