YNL077W

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Systematic name YNL077W
Gene name APJ1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:481392..482978
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Description of YNL077W: Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies[1][2]



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References

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  1. Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
  2. Kryndushkin DS, et al. (2002) Increased expression of Hsp40 chaperones, transcriptional factors, and ribosomal protein Rpp0 can cure yeast prions. J Biol Chem 277(26):23702-8 SGD PMID 11923285

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