YGR206W

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Systematic name YGR206W
Gene name MVB12
Aliases
Feature type ORF, Verified
Coordinates Chr VII:910437..910742
Primary SGDID S000003438


Description of YGR206W: ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome[1][2][3][4]




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References

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  1. Curtiss M, et al. (2007) Efficient Cargo Sorting by ESCRT-I and the Subsequent Release of ESCRT-I from Multivesicular Bodies Requires the Subunit Mvb12. Mol Biol Cell 18(2):636-45 SGD PMID 17135292
  2. Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 SGD PMID 15883373
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  4. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549

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