YMR020W
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| Systematic name | YMR020W | |
| Gene name | FMS1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XIII:315376..316902 | |
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Description of YMR020W: Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis[1][2][3]
Contents
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References
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- Jump up ↑ Chattopadhyay MK, et al. (2003) Spermidine but not spermine is essential for hypusine biosynthesis and growth in Saccharomyces cerevisiae: spermine is converted to spermidine in vivo by the FMS1-amine oxidase. Proc Natl Acad Sci U S A 100(24):13869-74 SGD PMID 14617780
- Jump up ↑ Landry J and Sternglanz R (2003) Yeast Fms1 is a FAD-utilizing polyamine oxidase. Biochem Biophys Res Commun 303(3):771-6 SGD PMID 12670477
- Jump up ↑ White WH, et al. (2001) Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine. J Biol Chem 276(14):10794-800 SGD PMID 11154694
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