YLR382C
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| Systematic name | YLR382C | |
| Gene name | NAM2 | |
| Aliases | MSL1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XII:884751..882067 | |
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Description of YLR382C: Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance[1][2][3][4]
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References
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- ↑ Rho SB and Martinis SA (2000) The bI4 group I intron binds directly to both its protein splicing partners, a tRNA synthetase and maturase, to facilitate RNA splicing activity. RNA 6(12):1882-94 SGD PMID 11142386
- ↑ Labouesse M, et al. (1985) The yeast nuclear gene NAM2 is essential for mitochondrial DNA integrity and can cure a mitochondrial RNA-maturase deficiency. Cell 41(1):133-43 SGD PMID 2986842
- ↑ Zagorski W, et al. (1991) Purification and characterization of the Saccharomyces cerevisiae mitochondrial leucyl-tRNA synthetase. J Biol Chem 266(4):2537-41 SGD PMID 1990003
- ↑ Labouesse M (1990) The yeast mitochondrial leucyl-tRNA synthetase is a splicing factor for the excision of several group I introns. Mol Gen Genet 224(2):209-21 SGD PMID 2277640
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