YLR376C

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Systematic name YLR376C
Gene name PSY3
Aliases
Feature type ORF, Uncharacterized
Coordinates Chr XII:873553..872825
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Description of YLR376C: Protein of unknown function; deletion results in a mutator phenotype suggesting a role for this protein as a mutational suppressor; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C [1][2]



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References

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  1. Wu HI, et al. (2004) Genome-wide identification of genes conferring resistance to the anticancer agents cisplatin, oxaliplatin, and mitomycin C. Cancer Res 64(11):3940-8 SGD PMID 15173006
  2. Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34 SGD PMID 12972632

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