YLR347C

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Systematic name YLR347C
Gene name KAP95
Aliases RSL1
Feature type ORF, Verified
Coordinates Chr XII:826412..823827
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Description of YLR347C: Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p) that mediates nuclear import of cargo proteins via a nuclear localization signal (NLS), interacts with nucleoporins to guide transport across the nuclear pore complex[1][2]



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References

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  1. Gilchrist D and Rexach M (2003) Molecular basis for the rapid dissociation of nuclear localization signals from karyopherin alpha in the nucleoplasm. J Biol Chem 278(51):51937-49 SGD PMID 14514698
  2. Aitchison JD, et al. (1996) Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins. Science 274(5287):624-7 SGD PMID 8849456

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