YLR304C
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Systematic name | YLR304C | |
Gene name | ACO1 | |
Aliases | GLU1 | |
Feature type | ORF, Verified | |
Coordinates | Chr XII:737550..735214 | |
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Description of YLR304C: Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy[1][2]
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References
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- ↑ Chen XJ, et al. (2005) Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307(5710):714-7 SGD PMID 15692048
- ↑ Gangloff SP, et al. (1990) Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate. Mol Cell Biol 10(7):3551-61 SGD PMID 1972545
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