YLR246W
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| Systematic name | YLR246W | |
| Gene name | ERF2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XII:627120..628199 | |
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Description of YLR246W: Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole[1][2][3]
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References
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- ↑ Roth AF, et al. (2006) Global analysis of protein palmitoylation in yeast. Cell 125(5):1003-13 SGD PMID 16751107
- ↑ Lobo S, et al. (2002) Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae. J Biol Chem 277(43):41268-73 SGD PMID 12193598
- ↑ Bartels DJ, et al. (1999) Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae. Mol Cell Biol 19(10):6775-87 SGD PMID 10490616
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