YLR174W

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Systematic name YLR174W
Gene name IDP2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:504593..505831
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Description of YLR174W: Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose[1][2]



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References

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  1. Haselbeck RJ and McAlister-Henn L (1993) Function and expression of yeast mitochondrial NAD- and NADP-specific isocitrate dehydrogenases. J Biol Chem 268(16):12116-22 SGD PMID 8099357
  2. Loftus TM, et al. (1994) Isolation, characterization, and disruption of the yeast gene encoding cytosolic NADP-specific isocitrate dehydrogenase. Biochemistry 33(32):9661-7 SGD PMID 8068643

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