YLR136C
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Systematic name | YLR136C | |
Gene name | TIS11 | |
Aliases | CTH2 | |
Feature type | ORF, Verified | |
Coordinates | Chr XII:416659..415802 | |
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Description of YLR136C: mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis[1][2][3]
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References
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- ↑ Puig S, et al. (2005) Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation. Cell 120(1):99-110 SGD PMID 15652485
- ↑ Ma Q and Herschman HR (1995) The yeast homologue YTIS11, of the mammalian TIS11 gene family is a non-essential, glucose repressible gene. Oncogene 10(3):487-94 SGD PMID 7845673
- ↑ Thompson MJ, et al. (1996) Cloning and characterization of two yeast genes encoding members of the CCCH class of zinc finger proteins: zinc finger-mediated impairment of cell growth. Gene 174(2):225-33 SGD PMID 8890739
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