YLR133W
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Systematic name | YLR133W | |
Gene name | CKI1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr XII:408446..410194 | |
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Description of YLR133W: Choline kinase, catalyzes the first step in the CDP-choline pathway phosphatidylcholine synthesis (Kennedy pathway); mRNA expression is regulated by inositol and choline, enzyme activity is stimulated by phosphorylation by protein kinase[1][2][3][4]
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References
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- Jump up ↑ Kim KH, et al. (1998) Expression, purification, and characterization of choline kinase, product of the CKI gene from Saccharomyces cerevisiae. J Biol Chem 273(12):6844-52 SGD PMID 9506987
- Jump up ↑ Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 SGD PMID 11078727
- Jump up ↑ Hosaka K, et al. (1989) Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli. J Biol Chem 264(4):2053-9 SGD PMID 2536698
- Jump up ↑ Hosaka K, et al. (1990) Repression of choline kinase by inositol and choline in Saccharomyces cerevisiae. J Bacteriol 172(4):2005-12 SGD PMID 2156807
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