YLL028W

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Systematic name YLL028W
Gene name TPO1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:84803..86563
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Description of YLL028W: Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane[1][2][3]



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References

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  1. Uemura T, et al. (2005) Characteristics of the polyamine transporter TPO1 and regulation of its activity and cellular localization by phosphorylation. J Biol Chem 280(10):9646-52 SGD PMID 15637075
  2. Tomitori H, et al. (2001) Multiple polyamine transport systems on the vacuolar membrane in yeast. Biochem J 353(Pt 3):681-8 SGD PMID 11171066
  3. Tomitori H, et al. (1999) Identification of a gene for a polyamine transport protein in yeast. J Biol Chem 274(6):3265-7 SGD PMID 9920864

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