YJL157C
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Systematic name | YJL157C | |
Gene name | FAR1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr X:126324..123832 | |
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Description of YJL157C: Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate[1][2][3][4]
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References
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- ↑ Henchoz S, et al. (1997) Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev 11(22):3046-60 SGD PMID 9367986
- ↑ Chang F and Herskowitz I (1990) Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2. Cell 63(5):999-1011 SGD PMID 2147873
- ↑ Nern A and Arkowitz RA (1999) A Cdc24p-Far1p-Gbetagamma protein complex required for yeast orientation during mating. J Cell Biol 144(6):1187-202 SGD PMID 10087263
- ↑ Peter M and Herskowitz I (1994) Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1. Science 265(5176):1228-31 SGD PMID 8066461
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