YGR087C
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| Systematic name | YGR087C | |
| Gene name | PDC6 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr VII:652985..651294 | |
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Description of YGR087C: Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, involved in amino acid catabolism[1][2][3][4][5][6][7]
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References
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- ↑ Dickinson JR, et al. (2003) The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. J Biol Chem 278(10):8028-34 SGD PMID 12499363
- ↑ Pronk JT, et al. (1996) Pyruvate metabolism in Saccharomyces cerevisiae. Yeast 12(16):1607-33 SGD PMID 9123965
- ↑ Hohmann S and Cederberg H (1990) Autoregulation may control the expression of yeast pyruvate decarboxylase structural genes PDC1 and PDC5. Eur J Biochem 188(3):615-21 SGD PMID 2185016
- ↑ Liesen T, et al. (1996) ERA, a novel cis-acting element required for autoregulation and ethanol repression of PDC1 transcription in Saccharomyces cerevisiae. Mol Microbiol 21(3):621-32 SGD PMID 8866484
- ↑ Hohmann S (1991) Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae. J Bacteriol 173(24):7963-9 SGD PMID 1744053
- ↑ Muller EH, et al. (1999) Thiamine repression and pyruvate decarboxylase autoregulation independently control the expression of the Saccharomyces cerevisiae PDC5 gene. FEBS Lett 449(2-3):245-50 SGD PMID 10338141
- ↑ Kellermann E, et al. (1986) Analysis of the primary structure and promoter function of a pyruvate decarboxylase gene (PDC1) from Saccharomyces cerevisiae. Nucleic Acids Res 14(22):8963-77 SGD PMID 3537965
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