YGL254W

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Systematic name YGL254W
Gene name FZF1
Aliases NRC299, RSU1, SUL1
Feature type ORF, Verified
Coordinates Chr VII:22304..23203
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Description of YGL254W: Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers[1][2][3]



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References

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  1. Breitwieser W, et al. (1993) Identification of a gene encoding a novel zinc finger protein in Saccharomyces cerevisiae. Yeast 9(5):551-6 SGD PMID 8322518
  2. Avram D, et al. (1999) Fzf1p of Saccharomyces cerevisiae is a positive regulator of SSU1 transcription and its first zinc finger region is required for DNA binding. Yeast 15(6):473-80 SGD PMID 10234785
  3. Avram D and Bakalinsky AT (1996) Multicopy FZF1 (SUL1) suppresses the sulfite sensitivity but not the glucose derepression or aberrant cell morphology of a grr1 mutant of Saccharomyces cerevisiae. Genetics 144(2):511-21 SGD PMID 8889516

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